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    Although available since 2003 in 5, 10, 20 mg dosage, in late 2008/early 2009, the U.S. FDA approved the commercial sale of Cialis Coupon in 2.5 mg dosage as a once-a-day treatment.

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    Cialis es un inhibidor eficaz, reversible, selectivo de la fosfodiesterasa de tipo 5 (PDE 5) específico para el monofosfato de guanosina cíclico (cGMP). Cuando la estimulación sexual causa la liberación local de óxido nítrico, la inhibición de la PDE 5 por Cialis lleva a un aumento de los niveles de cGMP en el cuerpo cavernoso.

    Cialis 5 mg for once daily use resulted in statistically significant improvements in the total IPSS and in the EF domain of the IIEF questionnaire. Cialis 5 mg for once daily use also resulted in statistically significant improvement in SEP3. Cialis 2.5 mg did not result in statistically significant improvement in the total.

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    Cialis is available in a variety of dosage strengths, including 2.5 mg, 5 mg, 10 mg, and 20 mg. Consult your healthcare provider to see if a lower dosage form may be appropriate.


    CIALIS 5 mg for once daily use resulted in statistically significant improvements in the total IPSS and in the EF domain of the IIEF questionnaire. CIALIS 5 mg for once daily use also resulted in statistically significant improvement in SEP3. CIALIS 2.5 mg did not result in statistically significant improvement in the total.

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